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HMPS differs from JP by the presence of lesser number of polyps (1-15), frequent adenomas and a later age of presentation.
It differs from familial adenomatous polyposis coli by the presence of mixed polyposis, absence of extracolonic lesions and APC mutations.
Contrast enhanced computerized tomography (CECT) scan of abdomen did not show any evidence of growth suggestive of colorectal malignancy, enlarged lymph node or metastasis.
He underwent total proctocolectomy with ileal pouch anal anastomosis (J-pouch). Small bowel, solid viscera, pelvis, peritoneum and omentum were grossly normal.
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At times, in a single patient, different polyps may show different histological subtypes or a single polyp may show multiple subtypes posing a diagnostic challenge to the clinician.
This form of mixed polyposis is now increasingly being recognised as a separate entity with an entirely different phenotype and presentation.
A 24 year male presented with history of bleeding per rectum for one and half years.
It was small in amount, reddish in colour and mixed with stools.
He was also symptomatic with generalised weakness and fatigue.